Warning: The doctor must comply with aseptic rules and the technique of intra-articular injection! Do not inject into glandular tissue. Do not mix in one procedure with products or preparations intended to restore the viscosity of the synovial fluid. Precautions: The treatment procedure is similar to other intraarticular injections carries a minimal risk of complications (inflammation, arthralgia, internal bleeding when injuring blood vessels, etc.). Follow the usual precautions: the introduction of NOLTREX- is possible only in clean dressing or operating rooms by qualified medical personnel. Use during pregnancy and lactation: Animal tests have shown reproductive function due to the use of NOLTREX-. The effect of the material on embryogenesis and lactation has not been studied. Adequate and strictly controlled studies in pregnant and lactating women have not been conducted. Pregnancy and lactation are not recommended.