Normal Serum Equine Origin

Normal Serum Equine Origin is a veterinary therapeutic product derived from healthy horse serum, designed to provide supportive therapy for various equine health conditions. For use as an aid in non-specific treatment of equine infections and disease conditions. Administration provides supplemental equine albumin, globulins and associated fluids.

Composition and Components

Primary Therapeutic Components:

Administration provides supplemental equine albumin and other essential serum proteins including:

Equine Albumin: Primary plasma protein maintaining oncotic pressure

Globulins: Including immunoglobulins for immune support

Associated Fluids: Natural plasma components

Electrolytes: Balanced electrolyte composition

Coagulation Factors: Natural clotting proteins

Protein Profile:

Normal equine serum contains the complete spectrum of equine-derived plasma proteins in their natural concentrations and ratios, providing physiologically appropriate supplementation.

Clinical Indications

Primary Therapeutic Uses:

For use as an aid in non-specific treatment of equine infections and disease conditions. Also recommended for non-specific treatment of haemorrhage, shock following injury, and debilitating conditions for which blood enrichment is desired.

Normal Serum Equine Origin Specific Applications:

Infectious Conditions:

Supportive therapy during bacterial or viral infections

Immune system support during illness

Non-specific resistance enhancement

Adjunct therapy with antimicrobials

Trauma and Emergency Care:

Hemorrhage management and volume replacement

Shock treatment following injury

Surgical support and recovery aid

Hypoproteinemia correction

Debilitating Conditions:

Chronic illness support

Protein deficiency states

Convalescence support

General health maintenance in compromised animals

Normal Serum Equine Origin Dosage and Administration

Administration Guidelines:

Inject subcutaneously, intramuscularly, or intravenously, 50 ml to 250 ml depending upon weight of animal and judgment of vet

Route Options:

Intravenous: Most rapid effect for emergency situations

Intramuscular: Sustained absorption for ongoing support

Subcutaneous: Slower absorption for maintenance therapy

Dosing Considerations:

Volume Range: 50-250 mL per treatment

Weight-Based: Dosing adjusted for animal size

Veterinary Judgment: Final dosing based on clinical assessment

Condition Severity: Dosage varies with disease severity

Clinical Benefits

Therapeutic Mechanisms:

Volume Expansion:

Plasma volume restoration in dehydrated or shocked animals

Oncotic pressure maintenance

Cardiovascular support during critical illness Normal Serum Equine Origin

Protein Supplementation:

Albumin replacement in hypoproteinemic animals

Globulin support for immune function

Nutritional protein support during illness

Immune Support:

Natural immunoglobulin supplementation

Enhanced resistance to secondary infections

Immune system modulation during stress

Safety Considerations

Important Safety Warning:

The use of equine serum has been associated with serum hepatitis in horses (Theiler’s Disease). If user has questions, consult a veterinarian.

Theiler’s Disease Risk:

Theiler’s Disease is a serious form of acute hepatic necrosis that can occur following administration of equine-origin serum products. This condition:

Can be fatal in severe cases

Occurs weeks to months after serum administration

Requires immediate veterinary attention if suspected

Risk varies among individual horses

Normal Serum Equine Origin Risk Mitigation:

Professional veterinary assessment before use

Careful patient selection and monitoring

Awareness of clinical signs of hepatic dysfunction

Prompt intervention if adverse effects occur

Professional Oversight

Veterinary Requirements:

Prescription veterinary medicine

Professional administration recommended

Pre-treatment health assessment

Post-treatment monitoring for adverse effects

Documentation of treatment and response

Clinical Monitoring:

Regular assessment of therapeutic response

Monitoring for signs of Theiler’s Disease

Liver function evaluation when indicated

Overall patient condition assessment

Historical Context

Regulatory Background:

This product was licensed prior to the requirement to establish a minimum age for use.  This indicates the product has a long history of veterinary use, predating modern regulatory requirements for age-specific safety data. Normal Serum Equine Origin

Storage and Handling

Product Specifications:

Sterile biological product requiring proper storage

Temperature-controlled storage typically required

Limited shelf life due to biological nature

Aseptic handling techniques essential

Modern Context

While normal serum equine origin remains available for veterinary use, modern veterinary medicine often employs more specific therapies such as:

Synthetic colloids for volume expansion

Specific immunoglobulin preparations

Targeted protein therapies

Species-specific plasma products

However, normal equine serum continues to serve as a valuable therapeutic option for supportive care in debilitated horses when used under appropriate veterinary supervision with full awareness of associated risks, particularly Theiler’s Disease.

The product represents a traditional but still relevant approach to providing comprehensive protein and immune support for horses requiring non-specific therapeutic intervention during illness or recovery periods. Normal Serum Equine Origin