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Acetaminophen, also known as Nimesulide Paracetamol Injection, is commonly used for its analgesic and antipyretic effects. Its therapeutic effects are similar to salicylates, but it lacks anti-inflammatory, antiplatelet, and gastric ulcerative effects. Nimesulide Paracetamol Injection Nimesulide Paracetamol Injection Nimesulide Paracetamol Injection. Buy Nimesulide Paracetamol online without prescription usa, Order Nimesulide Paracetamol online Alaska, what is Nimesulide Paracetamol, how to use Nimesulide Paracetamol, Is Nimesulide Paracetamol good for humans. how to use Nimesulide Paracetamol, Nimesulide Paracetamol for sale, looking for Nimesulide Paracetamol online, Nimesulide Paracetamol for horse, Best place to buy Nimesulide Paracetamol . Order Nimesulide Paracetamol near me, Buy Nimesulide Paracetamol online Arizona, dosage for Nimesulide Paracetamol , cheap Nimesulide Paracetamol, what is the cost of Nimesulide Paracetamol.
Nimesulide Paracetamol Injection is a relatively COX-2 selective, non-steroidal anti-inflammatory drug (NSAID) with analgesic and antipyretic properties. Its approved indications are the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old. Due to concerns about the risk of hepatotoxicity, nimesulide has been withdrawn from market in many countries
Acetaminophen, also known as Nimesulide Paracetamol Injection, is commonly used for its analgesic and antipyretic effects. Its therapeutic effects are similar to salicylates, but it lacks anti-inflammatory, antiplatelet, and gastric ulcerative effects. Nimesulide Paracetamol Injection Nimesulide Paracetamol Injection Nimesulide Paracetamol Injection
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SIDE EFFECTS of Nimesulide Paracetamol Injection
Oral TDLO (human): 1.429 mg/kg; Oral TDLO (woman): 2 mg/kg; Oral LD50 (rat): 200 mg/kg; Oral LD50 (mouse): 392 mg/kg.Oral, mouse: LD50 = 338 mg/kg; Oral, rat: LD50 = 1944 mg/kg. Acetaminophen is metabolize primarily in the liver, where most of it is convert to inactive compounds by conjugation with glucuronic acid and, to a lesser extent, sulfuric acid. Conjugates are then excrete by the kidneys. Only a small portion is excrete in unchanged in urine or oxidize via the hepatic cytochrome P450 enzyme system (CYP2E1). Metabolism via CYP2E1 produces a toxic metabolite, N-acetyl-p-benzoquinoneimine (NAPQI). The toxic effects of acetaminophen are due to NAPQI, not acetaminophen itself nor any of the major metabolites. At therapeutic doses, NAPQI reacts with the sulfhydryl group of glutathione to produce a non-toxic conjugate that is excrete by the kidneys. High doses of acetaminophen may cause glutathione depletion, accumulation of NAPQI and hepatic necrosis. The maximum daily dose of acetaminophen is 4 g. Liver failure has been observe at doses as low as 6 g per day. As such, the maximum daily and single dose of acetaminophen is currently being reviewed in some countries. N-acetyl-cysteine, a precursor of glutathione, may be administer in the event of acetaminophen toxicity. -
INDICATION for Nimesulide Paracetamol Injection
For the treatment of acute pain, the symptomatic treatment of osteoarthritis and primary dysmenorrhoea in adolescents and adults above 12 years old.Buy Nimesulide Paracetamol online without prescription usa, Order Paracetamol online Alaska, what is Nimesulide Paracetamol, how to use Nimesulide Paracetamol, Is Nimesulide Paracetamol good for humans. how to use Nimesulide Paracetamol, Nimesulide Paracetamol for sale
For temporary relief of fever, minor aches, and pains.
- Product Description of Nimesulide Paracetamol Injection
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Nimesulide Paracetamol Veterinary Injection
Brand Name:INSTA
Composition:
–Nimesulide 100 mg.
-Paracetamol 150 mg.
Indications:
-PUO
-Mastitis
-pain& fever
-lameness
-musculoskeletal disorder
Dosage & Pack:
-3-5 mg per kg body weight
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