Methio B12 Veterinary Injection

Methio B12 Veterinary Injection 50 mL containing Acetyl Methionine, l-Arginine and vitamin B12 for metabolic and hepatorenal disorders. Methio B12 is an adjunctive treatment for metabolic disorders and hepatorenal disorders in cattle, sheep, horses, pigs, and other veterinary species.

Active Ingredients and Composition

Based on the available information, Methio B12 contains:

Primary Active Components:

Acetyl Methionine (DL-Acetylmethionine) – Essential amino acid in acetylated form for better absorption

L-Arginine – Semi-essential amino acid supporting multiple physiological functions

Vitamin B12 (Cyanocobalamin/Hydroxocobalamin) – Essential for cellular metabolism and red blood cell formation Methio B12 Veterinary Injection 50 mL

Excipients:

Parahydroxybenzoate de méthyle sodique (E219) Parahydroxybenzoate de propyle sodique Hydroxyde de sodium Eau pour préparations injectables

Target Species and Therapeutic Applications

Approved Species:

les chiens, les chats, les bovins, les ovins, les chevaux, les porcins et les volailles

Cattle (beef and dairy)

Sheep and Goats

Horses (performance and breeding)

Pigs (production animals)

Dogs and Cats (companion animals)

Poultry (chickens, turkeys)

Primary Indications:

Traitement d’appoint des troubles métaboliques et des affections hépatorénales

Metabolic Disorders:

Ketosis in dairy cattle

Fatty liver syndrome

Metabolic acidosis

Energy metabolism disorders

Post-parturient metabolic stress

Hepatorenal Disorders:

Liver dysfunction and support

Kidney function impairment

Detoxification support

Hepatic lipidosis

Methio B12 Veterinary Injection 50 mL Additional Clinical Uses:

Appetite stimulation

Recovery from illness or surgery

Growth promotion in young animals

Stress-related conditions

Nutritional deficiency states

Performance enhancement support

Mechanism of Action

Acetyl Methionine Functions:

Liver Protection: Supports hepatic detoxification processes

Methyl Donor: Essential for numerous metabolic reactions

Antioxidant Properties: Helps protect against oxidative stress

Fat Metabolism: Assists in lipid metabolism and transport

L-Arginine Benefits:

Protein Synthesis: Essential for tissue repair and growth

Immune Function: Supports immune system activity

Wound Healing: Promotes tissue repair processes

Nitric Oxide Production: Supports vascular function

Ammonia Detoxification: Helps eliminate toxic ammonia Methio B12 Veterinary Injection 50 mL

Vitamin B12 Actions:

Red Blood Cell Formation: Essential for hematopoiesis

DNA Synthesis: Critical for cell division and growth

Nervous System Function: Maintains nerve health

Energy Metabolism: Cofactor in metabolic pathways

Protein Metabolism: Supports amino acid metabolism

Methio B12 Veterinary Injection 50 mL Dosage and Administration

Standard Dosing Guidelines:

Cattle, horses: 25 to 50 ml. Calves, pigs, sheep: 10 to 25 ml. Piglets, lambs, kids: 5 to 10 ml (estimated completion)

Large Animals:

Cattle (adult): 25-50 mL per animal

Horses (adult): 25-50 mL per animal

Medium Animals:

Calves: 10-25 mL per animal

Pigs (adult): 10-25 mL per animal

Sheep/Goats: 10-25 mL per animal

Small Animals:

Piglets, Lambs, Kids: 5-10 mL per animal

Dogs: 2-10 mL depending on size

Cats: 1-5 mL per animal

Poultry: 0.5-2 mL per bird Methio B12 Veterinary Injection 50 mL

Administration Routes:

Intravenous, intramuscular, subcutaneous or oral routes

Route Selection:

Intravenous: For rapid systemic effects, severe conditions

Intramuscular: Most common route, good absorption

Subcutaneous: Gentle administration, slower absorption

Oral: Alternative route, though less common for injections

Treatment Frequency:

Acute conditions: Daily for 3-7 days

Chronic conditions: Every 2-3 days for 1-2 weeks

Maintenance: Weekly or as needed

Prevention: Monthly during high-risk periods Methio B12 Veterinary Injection 50 mL

Clinical Benefits and Therapeutic Effects

Immediate Benefits:

Appetite Stimulation: Improved feed intake within 24-48 hours

Energy Enhancement: Increased vitality and activity levels

Metabolic Support: Rapid metabolic system support

Detoxification: Enhanced liver function

Long-term Benefits:

Improved Performance: Enhanced athletic ability in horses

Better Growth: Improved growth rates in young animals

Enhanced Recovery: Faster healing from illness or stress

Reproductive Support: Better fertility and reproductive success

General Health: Overall improvement in condition

Specific Clinical Applications:

Dairy Cattle:

Prevention and treatment of ketosis

Post-calving metabolic support

Milk production enhancement

Reproductive performance improvement

Methio B12 Veterinary Injection 50 mL Performance Horses:

Enhanced stamina and endurance

Faster recovery from training

Improved coat condition

Appetite stimulation during stress

Growing Animals:

Enhanced growth rates

Better feed conversion efficiency

Improved immune function

Reduced stress-related problems

Safety Profile and Contraindications

Generally Safe Profile:

Wide margin of safety

Well-tolerated across species

Low incidence of adverse reactions

Compatible with most medications

Potential Side Effects:

Local Reactions: Mild swelling at injection site

Allergic Reactions: Rare hypersensitivity responses

Overdose Effects: Generally well-tolerated even at high doses Methio B12 Veterinary Injection 50 mL

Contraindications:

Known hypersensitivity to any component

Severe cardiac dysfunction (use with caution)

Active bleeding disorders (due to arginine effects)

Withdrawal Periods and Food Safety

European Standards:

Bovins, ovins, caprins et équins : – viande et abats : zéro jour. – lait : zéro jour. Porcins : – viande et abats : zéro jour. Volailles : – viande et abats : zéro jour. – œuf : zéro jour

Zero Withdrawal Times for:

Cattle: Meat, organs, and milk

Sheep/Goats: Meat and organs

Horses: Meat and organs

Pigs: Meat and organs

Poultry: Meat, organs, and eggs

Note: Withdrawal periods may vary by jurisdiction – always consult local product labeling

Methio B12 Veterinary Injection 50 mL Storage and Handling

Storage Requirements:

Store at controlled room temperature (15-25°C)

Protect from direct sunlight

Do not freeze

Keep in original container

Maintain sterility until use

Handling Precautions:

Use sterile injection techniques

Allow to reach room temperature before injection

Shake gently if needed before use

Use appropriate needle sizes for species

Dispose of safely according to regulations

Drug Interactions and Compatibility

Generally Compatible With:

Most antibiotics and anti-inflammatory drugs

Other vitamin and mineral supplements

Supportive care medications

Fluid therapy solutions Methio B12 Veterinary Injection 50 mL

Considerations:

Monitor cumulative B-vitamin intake

Consider interactions with other methionine sources

May enhance effects of other metabolic supplements

Professional Use Guidelines

Veterinary Supervision:

Prescription medication requiring veterinary oversight

Professional diagnosis recommended before use

Monitoring of treatment response advised

Adjustment of dosing based on clinical response

Best Practices:

Accurate Diagnosis: Proper identification of metabolic disorders

Appropriate Dosing: Calculate based on species and condition

Proper Administration: Use correct injection techniques

Monitoring: Assess response and adjust treatment as needed

Record Keeping: Maintain detailed treatment records

Package Information

Size: 50 mL multi-dose vial Methio B12 Veterinary Injection 50 mL

Presentation: Sterile solution for injection

Shelf Life: Typically 2-3 years when properly stored

Usage: Multiple doses per vial depending on animal size

Regulatory Classification

Inscription au tableau des substances vénéneuses (Liste I / II). Classement du médicament en matière de délivrance

Prescription-Only Medicine (POM-V)

Controlled distribution through veterinary channels

Professional use only

Subject to veterinary oversight

Clinical Advantages

Comprehensive Metabolic Support:

Multi-modal Action: Addresses liver, kidney, and metabolic functions

Synergistic Formula: Components work together for enhanced benefits

Broad Species Application: Suitable for multiple animal types

Flexible Administration: Multiple injection routes available

Economic Benefits:

Improved Production: Better feed efficiency and growth

Reduced Treatment Costs: Prevention of metabolic disorders

Enhanced Performance: Better return on investment

Zero Withdrawal: Immediate market access for food animals

Methio B12 Veterinary Injection 50 mL represents a valuable metabolic support injection combining essential amino acids with vitamin B12 to provide comprehensive support for hepatorenal function and metabolic disorders across multiple veterinary species. Its zero withdrawal period and broad safety profile make it particularly useful in food-producing animals, while its metabolic benefits support performance and health in all treated species.