Dosage and Administration:
Oral Paste:

The usual dosage is 0.1 mg per kilogram of body weight once daily. This is typically a single dose administered via syringe for 14 consecutive days.
For a 1,100 lb (500 kg) horse, this would equate to a 50 mg dose once daily.
Tablets:
Equioxx chewable tablets are also dosed at 0.1 mg/kg once daily.
Injectable Solution:
Equioxx injectable is administered by a veterinarian. The usual dose is 0.09 mg/kg intravenously, typically used for the first day of treatment, followed by oral administration. Equine equioxx
It’s important to follow the veterinarian’s dosing instructions carefully and not exceed the recommended duration of treatment to avoid potential side effects.

Equioxx Injection (Firocoxib) Dosage:
Route of administration: Intravenous (IV) only.
Recommended dosage:
0.09 mg/kg (0.045 mg/lb) of body weight once daily for up to 5 days.
This means for a 500 kg (1,100 lb) horse, the injection dose would be around 45 mg of firocoxib administered intravenously once a day. equioxx pferd​

Equioxx Tablet (Chewable) Dosage:

Route of administration: Oral.
Recommended dosage:
0.1 mg/kg (0.045 mg/lb) of body weight once daily.
For a 500 kg (1,100 lb) horse, the dosage would be 50 mg of firocoxib once daily, which is typically a single chewable tablet.

Duration of Treatment:
The duration of treatment is generally up to 14 consecutive days for both forms. However, always follow the specific guidance of your veterinarian based on your horse’s condition.
Important Considerations:
Ensure accurate weight measurements for proper dosing.
Do not exceed the recommended dose or duration unless advised by your veterinarian.
If using both forms (injectable and oral), the veterinarian might begin with the injectable for the first few days, then transition to the oral tablets.

Duration of Use:
Equine equioxx is usually prescribed for short-term use (up to 14 days), but in some cases, veterinarians may extend its use based on the horse’s condition and response to treatment.
Benefits of Equioxx:
COX-2 Selectivity: Reduces pain and inflammation while minimizing the risk of gastric ulcers and kidney damage, which are common side effects of traditional NSAIDs.
Once-Daily Dosing: Convenient dosing makes it easy for horse owners to manage treatment.
Effective for Osteoarthritis: Proven to improve mobility and quality of life for horses suffering from osteoarthritis.
Potential Side Effects:
While Equioxx is considered safer than some traditional NSAIDs, it still has potential side effects, including:

Gastrointestinal Issues: Although less common than with other NSAIDs, horses on long-term Equioxx may still experience ulcers or colic.
Kidney Damage: Prolonged use can still affect kidney function, especially in dehydrated horses.
Lethargy or Decreased Appetite: Some horses may show signs of reduced appetite or lethargy while on Equioxx.
Weight Loss: Long-term use might cause unintended weight loss.

Precautions:

Avoid in Dehydrated Horses: Equioxx should not be given to dehydrated horses, as NSAIDs can potentially cause kidney issues in animals that are not well-hydrated.
Pre-existing Conditions: Horses with known renal, hepatic, or cardiac disease should be monitored closely when using Equioxx.
Pregnant or Lactating Mares: The safety of Equioxx has not been established in pregnant or lactating mares, so it should be used cautiously in these cases.
Veterinary Supervision:
It’s essential to use Equioxx under the supervision of a veterinarian, who can determine the appropriate dosage, monitor the horse’s response, and adjust treatment if necessary.
Conclusion:
Equine equioxx is a valuable tool in managing pain and inflammation, particularly for horses suffering from osteoarthritis. Its COX-2 selectivity makes it safer for long-term use than some other NSAIDs, though it still requires careful monitoring and veterinary oversight. Equioxx can help improve mobility and comfort in affected horses, enhancing their overall quality of life. equioxx pferd​

equioxx pferd​

Equine equioxx is a veterinary non-steroidal anti-inflammatory drug (NSAID) specifically formulated for horses. It contains firocoxib as the active ingredient and is used primarily for the treatment of pain and inflammation associated with osteoarthritis in horses. equioxx pferd​

Equioxx is particularly noted for being a COX-2 selective inhibitor, meaning it targets the enzyme responsible for inflammation and pain with less impact on the stomach lining and kidneys compared to traditional NSAIDs.

Key Information About Equioxx:
Active Ingredient:
Firocoxib: A selective COX-2 inhibitor that reduces the production of prostaglandins, which are involved in causing inflammation, pain, and fever. equioxx pferd​
Available Forms:
Equioxx Oral Paste: Administered via syringe, this paste is easy to dose and generally accepted by most horses.
Equioxx Tablets: These are chewable tablets that are also given orally.
Equioxx Injectable Solution: A solution for intravenous use, often administered by veterinarians, typically during acute stages of osteoarthritis or before transitioning to oral therapy.
Uses of Equioxx:

Treatment of Osteoarthritis:

Equine equioxx is primarily prescribed to reduce pain and inflammation associated with osteoarthritis in horses. It helps improve the horse’s comfort and mobility, making it an effective choice for managing chronic conditions where joint pain is a significant factor.
Post-Surgical Pain and Inflammation:

In some cases, Equioxx is used to manage pain and inflammation following surgery, particularly orthopedic procedures.
Acute and Chronic Pain Relief:

Horses experiencing acute pain from injury or strain, as well as those requiring long-term pain management due to chronic conditions like arthritis, can benefit from Equioxx.
How It Works:
Equioxx works by selectively inhibiting the COX-2 enzyme while sparing the COX-1 enzyme. This selectivity is important because COX-2 is primarily responsible for inflammation and pain, while COX-1 is involved in maintaining the protective lining of the stomach and other critical functions such as kidney protection. By targeting only COX-2, Equioxx provides anti-inflammatory benefits with reduced risk of gastric ulcers and kidney damage, common side effects of traditional NSAIDs.